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RA Capital Management, L.P.

All holdings · as of Mar 31, 2026

85 positions

CompanyClassValue ↓Shares% of portfolio
ASCENDIS PHARMA A/S—$2.35B10,281,49624.9%
VAXCYTE, INC.—$666.79M11,474,5997.1%
RHYTHM PHARMACEUTICALS, INC.—$579.81M6,666,8376.1%
Tyra Biosciences, Inc.—$467.21M12,198,6255.0%
Sionna Therapeutics, Inc.—$397.09M9,905,0454.2%
Edgewise Therapeutics, Inc.—$328.50M10,428,4373.5%
NEWAMSTERDAM PHARMA CO NV—$305.70M9,550,1913.2%
Nuvalent, Inc.—$259.62M2,534,1452.8%
Dianthus Therapeutics, Inc.—$219.18M2,611,7332.3%
MINERALYS THERAPEUTICS INCMLYSCommon Stock$208.40M7,692,7502.2%
SpyGlass Pharma, Inc.SGPCommon Stock$207.83M8,021,1172.2%
WAVE LIFE SCIENCES LTD—$195.57M26,975,5052.1%
Septerna, Inc.SEPNCommon Stock$168.11M6,995,8581.8%
Disc Medicine, Inc.IRONCommon Stock$156.67M2,450,2211.7%
Janux Therapeutics, Inc.—$155.54M11,189,6931.6%
BIOCRYST PHARMACEUTICALS INC—$150.67M15,827,1861.6%
Bicara Therapeutics Inc.—$144.32M7,255,9931.5%
Praxis Precision Medicines, Inc.—$120.43M373,7871.3%
GH RESEARCH PLC—$107.93M7,676,6971.1%
Zai Lab Limited—$107.35M5,707,2621.1%
Taysha Gene Therapies, Inc.TSHACommon Stock$105.29M23,555,6481.1%
Vor Biopharma Inc.—$96.43M5,404,9981.0%
GERON CORP—$95.02M63,771,3661.0%
ARS Pharmaceuticals, Inc.—$87.21M10,860,9770.9%
Sarepta Therapeutics, Inc.—$84.92M3,902,5960.9%
SPYRE THERAPEUTICS, INC.—$81.79M1,621,6200.9%
Evommune, Inc.EVMNCommon Stock$80.34M3,494,6380.9%
Climb Bio, Inc.CLYMCommon Stock$77.41M11,300,9390.8%
Solid Biosciences Inc.SLDBCommon Stock$67.25M9,339,9780.7%
Artiva Biotherapeutics, Inc.—$63.46M9,853,3020.7%
DAMORA THERAPEUTICS INC—$62.14M2,399,3100.7%
Xencor Inc—$59.06M4,897,2370.6%
LB PHARMACEUTICALS INCLBRXCommon Stock$54.46M2,208,6040.6%
JADE BIOSCIENCES, INC.—$51.58M3,671,0830.5%
Acumen Pharmaceuticals, Inc.—$49.54M20,992,6690.5%
4D MOLECULAR THERAPEUTICS, INC.—$47.01M5,049,7790.5%
Fulcrum Therapeutics, Inc.—$46.43M6,053,9600.5%
CAPRICOR THERAPEUTICS, INC.—$45.84M1,507,8440.5%
Century Therapeutics, Inc.IPSCCommon Stock$40.13M17,754,4300.4%
Olema Pharmaceuticals, Inc.—$38.77M2,600,0000.4%
LENZ Therapeutics, Inc.—$38.24M4,178,8230.4%
Monopar Therapeutics Inc.MNPRCommon Stock$36.56M667,2070.4%
PepGen Inc.—$35.51M20,064,5450.4%
Design Therapeutics, Inc.DSGNCommon Stock$31.63M2,972,9730.3%
Mirum Pharmaceuticals, Inc.—$29.43M318,5540.3%
BioAge Labs, Inc.BIOACommon Stock$28.87M1,650,6480.3%
Lexeo Therapeutics, Inc.—$28.70M5,000,0000.3%
ASSEMBLY BIOSCIENCES, INC.ASMBCommon Stock$28.32M1,020,4100.3%
Rezolute, Inc.—$28.00M9,180,0000.3%
Aktis Oncology, Inc.AKTSCommon Stock$26.89M1,503,0840.3%
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