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Palo Alto Investors LP

Quarter-over-quarter position changes

42 changes

ActionCompanyQuarter ↓Δ sharesΔ %Held afterFlowImpact
TrimmedAMICUS THERAPEUTICS INCMar 31, 2026-4,092,722-79%1,113,045$59.18Mhigh
AddedMirum Pharmaceuticals, Inc.Mar 31, 2026+168,754+108%325,175$15.59Mmedium
ExitedGossamer Bio, Inc.Mar 31, 2026-4,471,592-100%0$13.86Mmedium
TrimmedINSMED INCMar 31, 2026-74,213-15%415,269$12.14Mmedium
NewCelldex Therapeutics, Inc.Mar 31, 2026+296,408New296,408$9.40Mmedium
AddedACADIA Pharmaceuticals IncMar 31, 2026+388,664+16%2,872,695$8.65Mmedium
TrimmedBIOGEN INC.Mar 31, 2026-42,852-23%140,719$7.86Mmedium
TrimmedDenali Therapeutics Inc.Mar 31, 2026-406,657-63%234,582$7.81Mmedium
AddedDisc Medicine, Inc.IRONMar 31, 2026+84,263+27%401,719$5.39Mmedium
TrimmedCompass Therapeutics, Inc.Mar 31, 2026-1,017,915-40%1,514,504$5.38Mmedium
AddedBicara Therapeutics Inc.Mar 31, 2026+251,833+84%550,408$5.01Mmedium
AddedTravere Therapeutics, Inc.Mar 31, 2026+119,734+108%230,453$3.56Mlow
TrimmedBioMarin Pharmaceutical IncMar 31, 2026-61,074-8.2%685,182$3.45Mlow
AddedDyne Therapeutics, Inc.Mar 31, 2026+180,775+12%1,652,972$3.28Mlow
AddedAnnexon, Inc.Mar 31, 2026+563,898+24%2,948,090$3.12Mlow
TrimmedAnaptysBio, Inc.Mar 31, 2026-51,871-7.5%638,161$2.88Mlow
AddedUltragenyx Pharmaceutical Inc.Mar 31, 2026+135,201+29%596,495$2.83Mlow
AddedUnited Therapeutics CorpMar 31, 2026+4,623+7.9%62,809$2.74Mlow
TrimmedIOVANCE BIOTHERAPEUTICS, INC.Mar 31, 2026-767,113-11%6,349,563$2.69Mlow
TrimmedXenon Pharmaceuticals Inc.Mar 31, 2026-45,174-47%51,345$2.63Mlow
NewCytokinetics IncMar 31, 2026+32,195New32,195$2.12Mlow
AddedSyndax Pharmaceuticals IncMar 31, 2026+70,479+8.9%864,986$1.65Mlow
NewVerastem, Inc.Mar 31, 2026+246,093New246,093$1.30Mlow
AddedPTC Therapeutics IncMar 31, 2026+17,691+2.0%921,607$1.21Mlow
TrimmedPROTHENA CORP PUBLIC LTD COMar 31, 2026-111,942-8.5%1,208,568$1.09Mlow
NewMADRIGAL PHARMACEUTICALS, INC.Mar 31, 2026+1,787New1,787$935.4Klow
AddedCareDx, Inc.Mar 31, 2026+53,650+11%531,870$931.4Klow
AddedTaysha Gene Therapies, Inc.TSHAMar 31, 2026+208,187+18%1,391,382$930.6Klow
NewXeris Biopharma Holdings, Inc.Mar 31, 2026+104,410New104,410$605.6Klow
AddedStoke Therapeutics, Inc.Mar 31, 2026+12,609+18%84,631$410.5Klow
TrimmedNovoCure LtdMar 31, 2026-18,525-1.4%1,280,439$201.9Klow
AddedAclaris Therapeutics, Inc.Mar 31, 2026+46,590+3.0%1,613,430$174.7Klow
TrimmedNuvation Bio Inc.NUVBMar 31, 2026-29,233-5.4%508,846$125.4Klow
TrimmedAldeyra Therapeutics, Inc.Mar 31, 2026-69,756-31%155,709$117.9Klow
AddedCAPRICOR THERAPEUTICS, INC.Mar 31, 2026+3,459+1.5%229,763$105.2Klow
TrimmedBicycle Therapeutics plcBCYCMar 31, 2026-19,181-8.7%201,890$89.0Klow
Exited37148K209Mar 31, 2026-15,047-100%0$85.5Klow
TrimmedH17182108Mar 31, 2026-1,621-3.9%39,605$77.1Klow
TrimmedeHealth, Inc.Mar 31, 2026-48,632-3.2%1,482,797$62.7Klow
Exited00972G207Mar 31, 2026-146,024-100%0$42.2Klow
TrimmedPyxis Oncology, Inc.PYXSMar 31, 2026-26,911-2.6%1,010,510$39.3Klow
AddedAGIOS PHARMACEUTICALS, INC.Mar 31, 2026+1,102+0.5%213,601$37.3Klow
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