Companies / Denali Therapeutics Inc.

Denali Therapeutics Inc.

Nasdaq: DNLICIK 1714899SOUTH SAN FRANCISCO, CA

Financials · FY2025

Revenue$0
Net income$-512.54M
Total debt—
Cash$201.53M
Diluted EPS$-2.97
Shares outstanding159.8M

Ownership

159.8M shares outstanding · as of Jul 31, 2026
0.38%Insiders
Ownership
Insiders0.38%602,289
Institutions96.18%153,741,756
Public float3.44%5,503,358

% of common shares outstanding (exact, from the latest cover-page filing). Institutions are quarterly 13F snapshots; insiders reflect current officers & directors.

Insiders 9

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Insider% of sharesShares
Baker Bros. Advisors LPFormerDirector
2.14%3,422,366
Watts Ryan J.CEOPresident and CEO · Director
0.19%296,833
Schuth Alexander O.COFO and Secretary
0.18%282,828
Flatley Jay TDirector
0.01%22,628
667, L.P.FormerDirector
——
Baker Bros. Advisors (GP) LLCFormerDirector
——
Baker Brothers Life Sciences LPFormerDirector
——
Baker FelixFormerDirector
——
Baker JulianDirector
——

Institutional holders 263

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HolderValue% of shares
BlackRock, Inc.$360.76M8.77%
BAILLIE GIFFORD & CO$231.68M7.55%
Vanguard Group Inc$215.59M8.17%
State Street Corporation$181.31M4.41%
Temasek Holdings (Private) Limited$180.37M4.39%
Fmr LLC$100.66M3.81%
Norges Bank$84.52M3.20%
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC$82.28M3.12%
Baker Bros. Advisors LP$71.65M2.33%
Geode Capital Management, LLC$71.58M2.33%

Activity

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InsidersInstitutions
What insiders are doing in this stock (Form 4).
DateActorActionSecurityValueShares ΔPosition afterImpact
Jan 6, 2026Watts Ryan J.
CEO
SellCommon Stock$580.8K-35K
-10.60%
296,833
0.19% of shares
medium
Jan 6, 2026Schuth Alexander O.
Executive
SellCommon Stock$284.1K-17K
-5.74%
282,828
0.18% of shares
medium
Jun 3, 2026Flatley Jay T
Director
GrantCommon Stock$0+6K
+39.51%
22,628
0.01% of shares
low
Jun 3, 2026Baker Bros. Advisors LP
Director
GrantCommon Stock$0+6K
+0.19%
3,422,366
2.14% of shares
low
Jun 3, 2026Baker Bros. Advisors LP
Director
GrantCommon Stock$0+6K
+1.90%
343,275
0.21% of shares
low
Jan 3, 2026Schuth Alexander O.
Executive
GrantCommon Stock$0+58K
+23.81%
300,046
0.19% of shares
low
Jan 3, 2026Watts Ryan J.
CEO
GrantCommon Stock$0+79K
+31.20%
332,031
0.21% of shares
low
Jun 3, 2026Flatley Jay T
Director
GrantStock Option (right to buy)—+19K
19,226
0.01% of shares
low

5%+ ownership events

Schedule 13D / 13G
FilerStance% of classSharesDate
Vanguard Group IncPassive13G/A—0—

Securities

via CUSIP / OpenFIGI
SymbolTypeMarketCUSIPFIGI
DNLI——24823R105—