Institutions / HighVista Strategies LLC

HighVista Strategies LLC

CIK 1335325 · Institution · as of Mar 31, 2026
Portfolio value
$362.16M
Positions
156
As of
Mar 31, 2026

Portfolio trend

Portfolio value

$362.16M-6.7%
$388.31M$375.23M$362.16MQ4 '25Q1 '26

Positions

156+7.6%
156151145Q4 '25Q1 '26

Top holdings

Mar 31, 2026View all 156 →
CompanyClassValueShares% of portfolio
Invesco Db Commdy Indx Trck$30.61M1,057,2388.5%
Abivax SA$12.61M113,2543.5%
Praxis Precision Medicines, Inc.$8.48M26,3232.3%
Cogent Biosciences, Inc.$7.58M197,0512.1%
Spyre Therapeutics, Inc.$7.38M146,2642.0%
Vaxcyte, Inc.$7.24M124,6472.0%
Revolution Medicines, Inc.$6.74M69,3091.9%
Terns Pharmaceuticals, Inc.$6.03M114,3071.7%
Structure Therapeutics Inc.GPCRADR$5.97M123,9091.6%
Nuvalent, Inc.$5.80M56,6021.6%
Immunovant, Inc.IMVTCommon Stock$5.59M225,1391.5%
Soleno Therapeutics, Inc.$5.53M165,2271.5%
Tyra Biosciences, Inc.$5.03M131,3041.4%
Amylyx Pharmaceuticals, Inc.$4.89M352,0851.4%
Amazon.com Inc$4.66M22,3971.3%
Lb Pharmaceuticals IncLBRXCommon Stock$4.28M173,5951.2%
Relay Therapeutics, Inc.$4.20M421,8811.2%
Insmed Inc$3.98M24,3161.1%
NVIDIA Corp$3.91M22,4201.1%
Oruka Therapeutics, Inc.$3.87M78,9111.1%
Cytokinetics Inc$3.87M58,6431.1%
Liquidia CorpLQDACommon Stock$3.76M99,7441.0%
Ocular Therapeutix, Inc$3.74M441,5731.0%
Tarsus Pharmaceuticals, Inc.$3.68M52,4641.0%
BridgeBio Pharma, Inc.$3.68M49,5601.0%

Activity

InsidersInstitutions
This fund's 13F position changes — what it's buying and selling.
DateActionCompanyValueShares ΔPosition afterImpact
Q1 2026
as of
TrimCogent Biosciences, Inc.
Common stock
$-5.37M-140K
-41.47%
197,051
2.09% of portfolio
medium
Q1 2026
as of
Exit171757206
Common stock
$-5.06M-23K
-100.00%
0
medium
Q1 2026
as of
TrimRevolution Medicines, Inc.
Common stock
$-4.95M-51K
-42.36%
69,309
1.86% of portfolio
low
Q1 2026
as of
ExitArcellx, Inc.
Common stock
$-4.89M-75K
-100.00%
0
low
Q1 2026
as of
TrimViridian Therapeutics, Inc.
Common stock
$-4.66M-238K
-63.96%
134,229
0.72% of portfolio
low
Q1 2026
as of
Add00370M103
Common stock
$4.57M+41K
+56.89%
113,254
3.48% of portfolio
low
Q1 2026
as of
TrimApogee Therapeutics, Inc.
Common stock
$-4.50M-53K
-59.92%
35,761
0.83% of portfolio
low
Q1 2026
as of
TrimProtagonist Therapeutics Inc
Common stock
$-4.18M-40K
-53.97%
33,852
0.99% of portfolio
low
Q1 2026
as of
ExitAgios Pharmaceuticals, Inc.
Common stock
$-4.02M-148K
-100.00%
0
low
Q1 2026
as of
NewOruka Therapeutics, Inc.
Common stock
$3.87M+79K
78,911
1.07% of portfolio
low