Companies / Ionis Pharmaceuticals Inc / Activity
Activity — Ionis Pharmaceuticals Inc
165 moves.
Top impactInsider · CEO movesInsider · biggest buysInsider · biggest sellsInstitution · biggest movesInstitution · new positions
| Date | Actor | Action | Security | Value | Shares Δ | Position after | Impact |
|---|---|---|---|---|---|---|---|
| Q1 2026 as of | Two Sigma Investments, LP 13F manager | Add | Common stock | $240.21M | +3.2M +120.32% | 5,857,629 3.52% of shares | high |
| Q1 2026 as of | Royal Bank of Canada 13F manager | Add | Common stock | $201.47M | +2.7M +239.81% | 3,801,815 2.29% of shares | high |
| Q1 2026 as of | Millennium Management LLC 13F manager | Add | Common stock | $71.95M | +958K +1027.48% | 1,051,506 0.63% of shares | high |
| Q1 2026 as of | Geode Capital Management, LLC 13F manager | Add | Common stock | $64.00M | +835K +26.53% | 3,984,332 2.40% of shares | high |
| Q1 2026 as of | Nomura Holdings Inc 13F manager | Trim | Common stock | $-55.17M | -735K -86.56% | 114,080 0.07% of shares | high |
| Q4 2025 as of | Norges Bank 13F manager | Trim | Common stock | $-42.57M | -538K -62.70% | 320,160 0.19% of shares | medium |
| Q1 2026 as of | Perceptive Advisors LLC 13F manager | New | Common stock | $37.85M | +504K | 504,000 0.30% of shares | medium |
| Q1 2026 as of | Amundi 13F manager | Trim | Common stock | $-32.81M | -437K -94.80% | 23,958 0.01% of shares | medium |
| Q2 2026 as of | State Street Corporation 13F manager | Add | Common stock | $28.54M | +360K +9.06% | 4,334,848 2.61% of shares | medium |
| Q2 2026 as of | TimesSquare Capital Management, LLC 13F manager | Add | Common stock | $26.83M | +338K +122.75% | 614,070 0.37% of shares | medium |
| Q1 2026 as of | Norges Bank 13F manager | Exit | Common stock | $-25.33M | -320K -100.00% | 0 | medium |
| Q1 2026 as of | Arrowstreet Capital, Limited Partnership 13F manager | Trim | Common stock | $-24.44M | -325K -30.61% | 737,859 0.44% of shares | medium |
| Q1 2026 as of | Atle Fund Management AB 13F manager | Trim | Common stock | $-21.75M | -65K -69.83% | 27,873 0.02% of shares | medium |
| Q1 2026 as of | TimesSquare Capital Management, LLC 13F manager | New | Common stock | $20.70M | +276K | 275,674 0.17% of shares | medium |
| Q1 2026 as of | Baker Bros. Advisors LP 13F manager | Add | Common stock | $19.21M | +256K +14.28% | 2,047,727 1.23% of shares | medium |
| Q1 2026 as of | TD Asset Management Inc 13F manager | Trim | Common stock | $-18.26M | -243K -31.46% | 529,954 0.32% of shares | medium |
| Q2 2026 as of | Tweedy, Browne Co LLC 13F manager | Trim | Common stock | $-14.64M | -185K -7.49% | 2,280,311 1.37% of shares | medium |
| Q1 2026 as of | Hudson Bay Capital Management LP 13F manager | Trim | Common stock | $-13.51M | -180K -37.87% | 295,100 0.18% of shares | medium |
| Q1 2026 as of | Marshall Wace, LLP 13F manager | Trim | Common stock | $-12.09M | -161K -62.65% | 95,954 0.06% of shares | medium |
| Q1 2026 as of | BNP Paribas Financial Markets 13F manager | Add | Common stock | $10.88M | +145K +43.29% | 479,460 0.29% of shares | medium |
| Q1 2026 as of | Capital Fund Management S.A. 13F manager | New | Common stock | $10.68M | +142K | 142,201 0.09% of shares | medium |
| Q4 2025 as of | Barclays PLC 13F manager | Add | Common stock | $10.19M | +129K +18.04% | 842,871 0.51% of shares | medium |
| Q1 2026 as of | Balyasny Asset Management L.P. 13F manager | Exit | Common stock | $-9.54M | -121K -100.00% | 0 | medium |
| Q2 2025 as of | Barclays PLC 13F manager | Add | Common stock | $9.06M | +229K +64.79% | 583,266 0.35% of shares | medium |
| Q3 2025 as of | Barclays PLC 13F manager | Add | Common stock | $8.56M | +131K +22.42% | 714,048 0.43% of shares | medium |
| Q1 2025 as of | Barclays PLC 13F manager | Trim | Common stock | $-7.31M | -242K -40.62% | 353,937 0.21% of shares | medium |
| Q1 2026 as of | D. E. Shaw & Co., Inc. 13F manager | Add | Common stock | $7.27M | +97K +29.09% | 429,599 0.26% of shares | medium |
| Q1 2026 as of | Adage Capital Partners Gp, L.L.C. 13F manager | Trim | Common stock | $-6.76M | -90K -64.29% | 50,000 0.03% of shares | medium |
| Q2 2026 as of | Privium Fund Management B.V. 13F manager | Add | Common stock | $6.27M | +79K +32.85% | 319,924 0.19% of shares | medium |
| Q1 2026 as of | Renaissance Technologies LLC 13F manager | Add | Common stock | $6.15M | +82K +36.65% | 305,549 0.18% of shares | medium |
| Q1 2026 as of | Css LLC/IL 13F manager | New | Common stock | $5.94M | +79K | 79,093 0.05% of shares | medium |
| Q4 2025 as of | Bank of America Corp /De 13F manager | Trim | Common stock | $-5.67M | -72K -8.38% | 783,579 0.47% of shares | medium |
| Q1 2026 as of | Bridgewater Associates, LP 13F manager | Exit | Common stock | $-5.36M | -68K -100.00% | 0 | medium |
| Q1 2026 as of | Fideuram - Intesa Sanpaolo Private Banking S.p.a. 13F manager | Trim | Common stock | $-5.06M | -67K -55.38% | 54,269 0.03% of shares | medium |
| Q1 2026 as of | AllianceBernstein L.P. 13F manager | Add | Common stock | $4.65M | +59K +17.21% | 400,669 0.24% of shares | low |
| Q2 2026 as of | BlackRock, Inc. 13F manager | Add | Common stock | $4.50M | +57K +0.53% | 10,704,660 6.44% of shares | low |
| Q3 2023 as of | Barclays PLC 13F manager | Add | Common stock | $4.41M | +97K +17.95% | 639,553 0.38% of shares | low |
| Q1 2026 as of | Groupama Asset Managment 13F manager | Add | Common stock | $4.33M | +58K +7.52% | 824,540 0.50% of shares | low |
| Q1 2026 as of | First Trust Advisors LP 13F manager | Trim | Common stock | $-4.27M | -57K -10.83% | 468,363 0.28% of shares | low |
| Q1 2026 as of | Mariner, LLC 13F manager | Exit | Common stock | $-3.78M | -48K -100.00% | 0 | low |
| Q2 2023 as of | Barclays PLC 13F manager | Add | Common stock | $3.42M | +83K +18.18% | 542,232 0.33% of shares | low |
| Q2 2026 as of | Victory Capital Management, Inc. 13F manager | Trim | Common stock | $-3.39M | -43K -39.34% | 65,967 0.04% of shares | low |
| Q1 2024 as of | Barclays PLC 13F manager | Trim | Common stock | $-2.91M | -67K -10.41% | 577,387 0.35% of shares | low |
| Q1 2026 as of | Orion Porfolio Solutions, LLC 13F manager | Add | Common stock | $2.84M | +38K +160.22% | 61,344 0.04% of shares | low |
| Q1 2026 as of | California State Teachers Retirement System 13F manager | Add | Common stock | $2.43M | +32K +22.41% | 176,485 0.11% of shares | low |
| Q1 2026 as of | Great Lakes Advisors, LLC 13F manager | Trim | Common stock | $-2.27M | -30K -20.28% | 118,926 0.07% of shares | low |
| Q1 2026 as of | Intech Investment Management LLC 13F manager | Add | Common stock | $2.17M | +29K +301.11% | 38,515 0.02% of shares | low |
| Q1 2026 as of | Victory Capital Management, Inc. 13F manager | Add | Common stock | $2.10M | +28K +34.70% | 108,744 0.07% of shares | low |
| Q1 2026 as of | BLB&B Advisors, LLC 13F manager | Trim | Common stock | $-1.98M | -26K -42.83% | 35,170 0.02% of shares | low |
| Q4 2025 as of | Peak6 LLC 13F manager | Add | Common stock | $1.94M | +25K +401.34% | 30,642 0.02% of shares | low |