Companies / Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals Inc

Nasdaq: IONSCIK 874015CARLSBAD, CA
Insider flow · last 90 daysNet sells $1.19M

Financials · FY2025

Revenue$943.71M
Net income$-381.39M
Total debt$1.81B
Cash$350.06M
Diluted EPS$-2.38
Shares outstanding166.2M

Ownership

166.2M shares outstanding · as of Jul 23, 2026
0.60%Insiders
Ownership
Insiders0.60%997,018
10%+ / strategic5.48%9,108,019
Institutions101.70%169,001,442
Public float0.00%0

Reported holdings exceed shares outstanding — public float shown as 0; some positions may overlap or lag.

% of common shares outstanding (exact, from the latest cover-page filing). Institutions are quarterly 13F snapshots; insiders reflect current officers & directors.

Insiders 17

View all →
Insider% of sharesShares
Monia Brett PCEOChief Executive Officer · Director
0.15%242,662
Berthelsen Spencer RDirector
0.09%156,013
Hougen Elizabeth LEVP, Finance & CFO
0.05%82,660
Bennett C FrankEVP, Chief Scientific Officer
0.05%80,554
Birchler BrianEVP, Corp and Development Ops
0.04%66,598
Schneider EugeneEVP, Chf Clinical Develop Ofcr
0.04%63,890
O'Neil Patrick R.EVP CLO & General Counsel
0.04%62,211
Parshall B LynneDirector
0.03%51,344
Baroldi JosephEVP, Chief Business Officer
0.03%45,664
Loscalzo JosephDirector
0.02%36,330

Institutional holders 500

View all →
HolderValue% of shares
Fmr LLC$1.90B14.49%
Capital World Investors$1.42B10.81%
Vanguard Group Inc$1.30B9.89%
BlackRock, Inc.$848.77M6.44%
Wellington Management Group LLP$495.25M3.77%
Two Sigma Investments, LP$439.85M3.52%
Bellevue Group AG$379.90M2.89%
State Street Corporation$343.71M2.61%
Geode Capital Management, LLC$305.20M2.40%
Royal Bank of Canada$285.48M2.29%

Activity

View all →
InsidersInstitutions
What insiders are doing in this stock (Form 4).
DateActorActionSecurityValueShares ΔPosition afterImpact
Mar 16, 2026Hougen Elizabeth L
Executive
SellCommon Stock$14.88M-206K
-66.78%
102,272
0.06% of shares
high
Mar 9, 2026Monia Brett P
CEO
SellCommon Stock$8.85M-118K
-32.49%
244,346
0.15% of shares
medium
Mar 3, 2026Bennett C Frank
Executive
SellCommon Stock$5.66M-72K
-43.23%
94,043
0.06% of shares
medium
Jan 30, 2026Monia Brett P
CEO
SellCommon Stock$5.21M-63K
-18.15%
283,927
0.17% of shares
medium
Mar 9, 2026Monia Brett P
CEO
ExerciseCommon Stock$4.48M+74K
+24.86%
369,332
0.22% of shares
low
May 4, 2026Loscalzo Joseph
Director
SellCommon Stock$4.46M-60K
-52.38%
54,111
0.03% of shares
medium
Feb 2, 2026Bennett C Frank
Executive
SellCommon Stock$4.04M-49K
-37.72%
80,293
0.05% of shares
medium
Mar 16, 2026Hougen Elizabeth L
Executive
ExerciseCommon Stock$3.67M+60K
+45.38%
193,180
0.12% of shares
low

5%+ ownership events

Schedule 13D / 13G
FilerStance% of classSharesDate
Vanguard Group IncPassive13G/A—0—
Capital World InvestorsPassive13G/A———
T. Rowe Price Investment Management, Inc.Passive13G/A—9,108,019—

Securities

via CUSIP / OpenFIGI
SymbolTypeMarketCUSIPFIGI
IONS——462222100—