Companies / Upstream Bio, Inc. / Activity
Activity — Upstream Bio, Inc.
54 moves.
Top impactInsider · CEO movesInsider · biggest buysInsider · biggest sellsInstitution · biggest movesInstitution · new positions
| Date | Actor | Action | Security | Value | Shares Δ | Position after | Impact |
|---|---|---|---|---|---|---|---|
| Q2 2026 as of | Covestor Ltd 13F manager | New | Common Stock | $0 | +39 | 39 <0.01% of shares | low |
| Q4 2025 as of | IFP Advisors, Inc 13F manager | Trim | Common Stock | $-27 | -1 -50.00% | 1 <0.01% of shares | low |
| Q2 2026 as of | SG Americas Securities, LLC 13F manager | New | Common Stock | $141 | +20K | 20,338 0.04% of shares | low |
| Q1 2026 as of | SG Americas Securities, LLC 13F manager | Exit | Common Stock | $-150 | -6K -100.00% | 0 | low |
| Q1 2026 as of | Gsa Capital Partners LLP 13F manager | New | Common Stock | $353 | +39K | 39,232 0.07% of shares | low |
| Q2 2026 as of | Gf Fund Management Co. Ltd. 13F manager | Add | Common Stock | $581 | +84 +7.92% | 1,145 <0.01% of shares | low |
| Q1 2026 as of | Natixis 13F manager | New | Common Stock | $1.1K | +120 | 120 <0.01% of shares | low |
| Q1 2026 as of | MAI Capital Management 13F manager | New | Common Stock | $1.5K | +171 | 171 <0.01% of shares | low |
| Q2 2026 as of | The PNC Financial Services Group, Inc. 13F manager | Add | Common Stock | $1.9K | +281 +265.09% | 387 <0.01% of shares | low |
| Q1 2026 as of | Rhumbline Advisers 13F manager | Trim | Common Stock | $-2.9K | -320 -0.77% | 41,203 0.08% of shares | low |
| Q1 2026 as of | ALPS Advisors, Inc. 13F manager | Trim | Common Stock | $-3.5K | -384 -0.87% | 43,992 0.08% of shares | low |
| Q1 2026 as of | Zurcher Kantonalbank (Zurich Cantonalbank) 13F manager | New | Common Stock | $4.3K | +477 | 477 <0.01% of shares | low |
| Q1 2026 as of | Sterling Capital Management LLC 13F manager | Trim | Common Stock | $-7.4K | -825 -42.99% | 1,094 <0.01% of shares | low |
| Q1 2025 as of | Barclays PLC 13F manager | Trim | Common Stock | $-12.4K | -2K -7.49% | 24,993 0.05% of shares | low |
| Q1 2026 as of | Royal Bank of Canada 13F manager | Exit | Common Stock | $-26.0K | -969 -100.00% | 0 | low |
| Q2 2026 as of | Persistent Asset Partners Ltd 13F manager | Trim | Common Stock | $-28.0K | -4K -45.49% | 4,855 <0.01% of shares | low |
| Q1 2026 as of | Bank of New York Mellon Corp/The 13F manager | Trim | Common Stock | $-31.2K | -3K -4.09% | 81,383 0.15% of shares | low |
| Q2 2026 as of | Quadrature Capital Ltd 13F manager | New | Common Stock | $124.5K | +18K | 17,988 0.03% of shares | low |
| Q2 2026 as of | WINTON GROUP Ltd 13F manager | New | Common Stock | $137.0K | +20K | 19,800 0.04% of shares | low |
| Q1 2026 as of | Mariner, LLC 13F manager | Add | Common Stock | $139.4K | +15K +130.89% | 27,314 0.05% of shares | low |
| Q3 2025 as of | Barclays PLC 13F manager | Trim | Common Stock | $-219.6K | -12K -12.04% | 85,315 0.16% of shares | low |
| Q1 2026 as of | California State Teachers Retirement System 13F manager | Add | Common Stock | $225.1K | +25K +170.69% | 39,661 0.07% of shares | low |
| Q1 2026 as of | ProShare Advisors LLC 13F manager | Exit | Common Stock | $-226.8K | -8K -100.00% | 0 | low |
| Q1 2026 as of | Victory Capital Management, Inc. 13F manager | New | Common Stock | $232.8K | +26K | 25,866 0.05% of shares | low |
| Q2 2026 as of | Victory Capital Management, Inc. 13F manager | Exit | Common Stock | $-232.8K | -26K -100.00% | 0 | low |
| Q4 2025 as of | Persistent Asset Partners Ltd 13F manager | New | Common Stock | $241.8K | +9K | 8,907 0.02% of shares | low |
| Q1 2026 as of | Intech Investment Management LLC 13F manager | Exit | Common Stock | $-282.3K | -10K -100.00% | 0 | low |
| Q1 2026 as of | Two Sigma Investments, LP 13F manager | Exit | Common Stock | $-285.1K | -11K -100.00% | 0 | low |
| Q1 2026 as of | Graham Capital Management, L.P. 13F manager | Exit | Common Stock | $-372.3K | -14K -100.00% | 0 | low |
| Q1 2026 as of | AQR Capital Management, LLC 13F manager | Add | Common Stock | $375.0K | +42K +136.60% | 72,171 0.13% of shares | low |
| Q1 2026 as of | Profund Advisors LLC 13F manager | Exit | Common Stock | $-395.9K | -15K -100.00% | 0 | low |
| Q1 2026 as of | Renaissance Technologies LLC 13F manager | Add | Common Stock | $411.3K | +46K +278.66% | 62,100 0.11% of shares | low |
| Q4 2024 as of | Barclays PLC 13F manager | New | Common Stock | $444.2K | +27K | 27,017 0.05% of shares | low |
| Q1 2026 as of | Prelude Capital Management, LLC 13F manager | Exit | Common Stock | $-449.6K | -17K -100.00% | 0 | low |
| Q2 2026 as of | Deutsche Bank AG 13F manager | Add | Common Stock | $786.3K | +114K +88.90% | 241,447 0.44% of shares | low |
| Q2 2025 as of | Barclays PLC 13F manager | Add | Common Stock | $790.5K | +72K +288.07% | 96,990 0.18% of shares | low |
| Q4 2025 as of | Bank of America Corp /De 13F manager | Add | Common Stock | $839.2K | +31K +55.72% | 86,384 0.16% of shares | low |
| Q1 2026 as of | Geode Capital Management, LLC 13F manager | Add | Common Stock | $888.6K | +99K +11.59% | 950,617 1.74% of shares | low |
| Q1 2026 as of | Rafferty Asset Management, LLC 13F manager | Exit | Common Stock | $-1.05M | -39K -100.00% | 0 | low |
| Q1 2026 as of | BNP Paribas Financial Markets 13F manager | Add | Common Stock | $1.09M | +121K +2432.15% | 126,000 0.23% of shares | low |
| Q1 2026 as of | Arrowstreet Capital, Limited Partnership 13F manager | New | Common Stock | $1.67M | +185K | 185,087 0.34% of shares | low |
| Q1 2026 as of | Marshall Wace, LLP 13F manager | Trim | Common Stock | $-2.49M | -277K -80.58% | 66,770 0.12% of shares | low |
| Q2 2026 as of | BlackRock, Inc. 13F manager | Add | Common Stock | $2.83M | +409K +12.22% | 3,753,358 6.85% of shares | low |
| Q1 2026 as of | Millennium Management LLC 13F manager | Add | Common Stock | $3.78M | +420K +81.21% | 937,323 1.71% of shares | low |
| Q2 2026 as of | State Street Corporation 13F manager | Trim | Common Stock | $-3.83M | -553K -41.91% | 766,323 1.40% of shares | low |
| Q4 2025 as of | Boxer Capital Management, LLC 13F manager | New | Common Stock | $4.07M | +150K | 150,000 0.27% of shares | low |
| Q1 2026 as of | D. E. Shaw & Co., Inc. 13F manager | Add | Common Stock | $7.14M | +793K +2928.61% | 820,480 1.50% of shares | medium |
| Q1 2026 as of | Great Point Partners, LLC 13F manager | Exit | Common Stock | $-8.14M | -300K -100.00% | 0 | medium |
| Q1 2026 as of | Altshuler Shaham Ltd 13F manager | Trim | Common Stock | $-8.65M | -961K -71.67% | 380,061 0.69% of shares | medium |
| Q1 2026 as of | Federated Hermes Inc 13F manager | Add | Common Stock | $8.81M | +979K +203169.29% | 979,758 1.79% of shares | medium |