Companies / ZYMEWORKS INC. / Institutional holders

Zymeworks Inc.

Institutional holders · 13F as of Dec 31, 2025

Holder	Value	Shares	% of shares
EcoR1 Capital, LLC	$604.81M	22,970,388	32.37%
Rubric Capital Management LP	$151.40M	5,750,000	8.10%
BlackRock, Inc.	$111.12M	4,251,030	5.99%
BVF INC/IL	$93.50M	3,734,142	5.26%
Perceptive Advisors LLC	$87.89M	3,510,078	4.95%
Morgan Stanley	$68.28M	2,593,080	3.65%
VANGUARD GROUP INC	$61.32M	2,328,727	3.28%
Siren, L.L.C.	$44.24M	1,680,121	2.37%
Dimensional Fund Advisors LP	$30.52M	1,159,215	1.63%
Nextech Invest, Ltd.	$29.33M	1,113,946	1.57%
STATE STREET CORPORATION	$28.45M	1,088,216	1.53%
Capricorn Fund Managers Ltd	$26.93M	1,022,840	1.44%
Vestal Point Capital, LP	$22.78M	865,000	1.22%
Arrowstreet Capital, Limited Partnership	$18.63M	743,898	1.05%
ADAGE CAPITAL PARTNERS GP, L.L.C.	$17.47M	663,546	0.94%
Nuveen, LLC	$17.07M	648,326	0.91%
Assenagon Asset Management S.A.	$17.05M	647,374	0.91%
GEODE CAPITAL MANAGEMENT, LLC	$16.52M	659,940	0.93%
FMR LLC	$14.75M	560,086	0.79%
Prosight Management, LP	$13.97M	530,393	0.75%
Redmile Group, LLC	$12.95M	491,654	0.69%
Qube Research & Technologies Ltd	$12.49M	474,290	0.67%
THE GOLDMAN SACHS GROUP, INC.	$11.06M	420,207	0.59%
DEUTSCHE BANK AG	$10.38M	397,190	0.56%
Hillsdale Investment Management Inc.	$8.65M	345,622	0.49%
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	$8.43M	320,261	0.45%
NORTHERN TRUST CORP	$8.11M	307,979	0.43%
Schonfeld Strategic Advisors LLC	$7.60M	288,571	0.41%
UBS Group AG	$7.34M	278,854	0.39%
Invesco Ltd.	$6.78M	257,580	0.36%
Citadel Advisors LLC	$6.72M	255,351	0.36%
Picton Mahoney Asset Management	$6.45M	244,798	0.34%
Granahan Investment Management, LLC	$6.28M	250,773	0.35%
SummitTX Capital, L.P.	$5.90M	224,268	0.32%
D. E. Shaw & Co., Inc.	$5.90M	235,621	0.33%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	$5.82M	220,909	0.31%
Renaissance Technologies LLC	$5.82M	220,877	0.31%
WELLS FARGO & COMPANY/MN	$5.48M	208,313	0.29%
RAYMOND JAMES FINANCIAL INC	$4.94M	187,685	0.26%
Wellington Management Group LLP	$4.78M	181,705	0.26%
SUSQUEHANNA INTERNATIONAL GROUP, LLP	$4.64M	176,088	0.25%
Federated Hermes Inc	$4.57M	182,410	0.26%
SILVERCREST ASSET MANAGEMENT GROUP LLC	$4.10M	163,649	0.23%
KENNEDY CAPITAL MANAGEMENT LLC	$3.83M	145,534	0.21%
Jupiter Asset Management Ltd	$3.30M	125,506	0.18%
Bank of New York Mellon Corp/The	$3.11M	124,105	0.17%
AMERIPRISE FINANCIAL INC	$2.98M	113,141	0.16%
CITIGROUP INC	$2.93M	111,207	0.16%
Opaleye Management Inc.	$2.87M	108,929	0.15%
Trexquant Investment LP	$2.67M	101,274	0.14%