| The Column Group IV GP, LP | 10% owner | 10.68% | 5,780,143 | Feb 6, 2026 |
| Lux Venture Partners V, LLC | 10% owner | 4.24% | 2,294,653 | Feb 6, 2026 |
| Wolfe Josh | Director · 10% owner | 4.24% | 2,294,653 | Feb 6, 2026 |
| Foresite Capital Management IV, LLC | 10% owner | 2.44% | 1,318,983 | Feb 4, 2026 |
| PERLMUTTER ROGER M | See remarks · Director | 0.53% | 284,857 | Mar 2, 2026 |
| FRAZIER KENNETH C | Director | 0.21% | 111,111 | Mar 2, 2026 |
| Baynes Roy D. | Chief Medical Officer | — | — | Mar 2, 2026 |
| Bowie Alfred Lloyd Jr. | Chief Financial Officer | — | — | Mar 2, 2026 |
| Chen Leon | Director | — | — | — |
| Column Group IV-A, LP | 10% owner | — | — | — |
| Column Group IV, LP | 10% owner | — | — | — |
| Column Group Opportunity III GP, LP | 10% owner | — | — | — |
| Column Group Opportunity III, LP | 10% owner | — | — | — |
| Foresite Capital Fund IV, L.P. | 10% owner | — | — | — |
| Foresite Capital Fund V, L.P. | 10% owner | — | — | — |
| Foresite Capital Management V, LLC | 10% owner | — | — | — |
| Foresite Capital Opportunity Fund V, L.P. | 10% owner | — | — | — |
| Foresite Capital Opportunity Management V, LLC | 10% owner | — | — | — |
| Foresite Capital VI-A, LLC | 10% owner | — | — | — |
| Foresite Capital VI-A Management, LLC | 10% owner | — | — | — |
| Hebert Peter | 10% owner | — | — | — |
| Huffines Robert Luther | Director | — | — | Mar 2, 2026 |
| Klobuchar Michael A | Chief Operating Officer | — | — | Mar 2, 2026 |
| Kutzkey Tim | 10% owner | — | — | — |
| Lux Co-Invest Opportunities II, L.P. | 10% owner | — | — | — |
| Lux Total Opportunities, L.P. | 10% owner | — | — | — |
| Lux Ventures V, L.P. | 10% owner | — | — | — |
| Meline David W | Director | — | — | — |
| Svennilson Peter | 10% owner | — | — | — |
| TCG Opportunity III GP, LLC | 10% owner | — | — | — |
| Thorner Benjamin Bruno | See Remarks | — | — | Mar 2, 2026 |