Companies / Spero Therapeutics, Inc.

Spero Therapeutics, Inc.

Nasdaq: SPROCIK 1701108CAMBRIDGE, MA

Financials · FY2025

Revenue$66.80M
Net income$8.57M
Total debt—
Cash$50.77M
Diluted EPS$0.15
Shares outstanding58.2M

Ownership

58.2M shares outstanding · as of Aug 7, 2026
3.5%Insiders
Ownership
Insiders3.48%2,026,051
Institutions37.56%21,874,275
Public float58.96%34,334,501

% of common shares outstanding (exact, from the latest cover-page filing). Institutions are quarterly 13F snapshots; insiders reflect current officers & directors.

Insiders 5

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Insider% of sharesShares
Rajavelu EstherSee Remarks
1.74%1,012,091
Keutzer TimothyChief Operating Officer
1.28%742,506
Deshpande MilindDirector
0.17%101,454
Pottage John C JrDirector
0.15%85,000
Thomas Frank EDirector
0.15%85,000

Institutional holders 58

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HolderValue% of shares
Gsk PLC$21.51M15.78%
Pfizer Inc$5.50M4.06%
Vanguard Group Inc$4.85M3.58%
Renaissance Technologies LLC$2.78M2.04%
Two Sigma Investments, LP$2.07M1.52%
Alphabet Inc.$1.97M1.53%
Anson Funds Management LP$1.46M1.07%
BlackRock, Inc.$1.31M1.02%
Geode Capital Management, LLC$1.22M0.89%
Citadel Advisors LLC$927.0K0.68%

Activity

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InsidersInstitutions
What insiders are doing in this stock (Form 4).
DateActorActionSecurityValueShares ΔPosition afterImpact
Feb 6, 2026Rajavelu Esther
Executive
SellCommon Stock$119.9K-51K
-4.78%
1,012,091
1.74% of shares
medium
Feb 6, 2026Rajavelu Esther
Executive
SellCommon Stock$87.6K-37K
-3.37%
1,062,907
1.83% of shares
low
Feb 3, 2026Keutzer Timothy
Executive
SellCommon Stock$51.8K-24K
-3.07%
764,629
1.31% of shares
low
Feb 6, 2026Keutzer Timothy
Executive
SellCommon Stock$44.0K-19K
-2.45%
742,506
1.28% of shares
low
Feb 2, 2026Keutzer Timothy
Executive
SellCommon Stock$41.6K-19K
-2.34%
788,853
1.35% of shares
low
Feb 2, 2026Rajavelu Esther
Executive
SellCommon Stock$40.6K-18K
-1.65%
1,100,008
1.89% of shares
low
Feb 4, 2026Keutzer Timothy
Executive
SellCommon Stock$7.8K-3K
-0.45%
761,158
1.31% of shares
low
Jun 23, 2026Deshpande Milind
Director
GrantCommon Stock$0+10K
+10.93%
101,454
0.17% of shares
low

Securities

via CUSIP / OpenFIGI
SymbolTypeMarketCUSIPFIGI
SPROCommon StockEquity84833T103BBG00HXSJ1R2